Colorado City is a city in and the county seat of Mitchell County, Texas, United States. The population was 4,146 at the 2010 census. Colorado City is located at 32°23′46″N 100°51′44″W (32.396163, -100.862137). According to the United States Census Bureau, the city has a total area of 5.3 square miles (14 km2), all of it land. Colorado City is situated along the Colorado River to the west and Lone Wolf Creek to the east.